Carbapenemase producing enterobacteriacae rectal colonization in dialysis patients: a large monocentric retrospective analysis

Carbapenemase-producing Enterobacteriaceae (CPE) represent a growing global public health concern due to their increasing prevalence and resistance to carbapenems, a group of last-resort antibiotics. Dialysis patients, who often have compromised immune systems, are particularly vulnerable to infections that represent the second cause of death in dialysis’ cohorts. Presenting a rectal colonization by CPE has a significative impact on patients in dialysis? Are there factors that can help us understand which patients are at a higher risk of developing CPE colonization? How can we treat a CPE colonized patient who develop fever? Our study aim to reviews the challenges posed by CPE in dialysis settings and explores current diagnostic, therapeutic, and infection control strategies on a large cohort of dialyzed patients.