Enabling a direct path from end-user specifications to executable protocols in a biology laboratory environment

Maccagnan, Alessandro (2012) Enabling a direct path from end-user specifications to executable protocols in a biology laboratory environment, [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Informatica, 23 Ciclo. DOI 10.6092/unibo/amsdottorato/4620.
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Biomedical analyses are becoming increasingly complex, with respect to both the type of the data to be produced and the procedures to be executed. This trend is expected to continue in the future. The development of information and protocol management systems that can sustain this challenge is therefore becoming an essential enabling factor for all actors in the field. The use of custom-built solutions that require the biology domain expert to acquire or procure software engineering expertise in the development of the laboratory infrastructure is not fully satisfactory because it incurs undesirable mutual knowledge dependencies between the two camps. We propose instead an infrastructure concept that enables the domain experts to express laboratory protocols using proper domain knowledge, free from the incidence and mediation of the software implementation artefacts. In the system that we propose this is made possible by basing the modelling language on an authoritative domain specific ontology and then using modern model-driven architecture technology to transform the user models in software artefacts ready for execution in a multi-agent based execution platform specialized for biomedical laboratories.

Tipologia del documento
Tesi di dottorato
Maccagnan, Alessandro
Dottorato di ricerca
Scuola di dottorato
Scienze e ingegneria dell'informazione
Settore disciplinare
Settore concorsuale
Parole chiave
Model-driven engineering, Ontology, Multi-agent system, LIMS, Biological protocol, Biology
Data di discussione
10 Maggio 2012

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