Novel Asymmetric Organocatalytic Transformations: Development, Optimization and Transformations

Bertuzzi, Giulio (2019) Novel Asymmetric Organocatalytic Transformations: Development, Optimization and Transformations, [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Chimica, 31 Ciclo.
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The developement of novel organocatalytic transformations is described. The elaborate mainly focuses on two catheories of organic reactions, namely azinium cations functionalizations (dearomatizations and aromatic subsititutions) and higher order cycloadditions. Particular attention has been devoted at the study and optimization of the reaction conditions and catalyst structure, in order to maximize yield and enantiopurity of the products as well as minimizing the catalyst loading and using the mildest conditions. The substrate scope of asymmetric reactions has always been thoroughly investigated to demonstrate the broad applicability of the proposed transformations, as well as the performance of synthetic elaborations illustrating the usefulness of the developed methods

Tipologia del documento
Tesi di dottorato
Bertuzzi, Giulio
Dottorato di ricerca
Settore disciplinare
Settore concorsuale
Parole chiave
Organocatalysis, N-alkylpridinium salts, Isoquinoline N-oxides, aldehydes, Higher Order Cycloadditions, Isobenzofulvenes, Pyrroles.
Data di discussione
4 Aprile 2019

Altri metadati

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