Modelli per lo studio dell'attività neuronale durante task cognitivi

Zavaglia, Melissa (2008) Modelli per lo studio dell'attività neuronale durante task cognitivi, [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Bioingegneria, 20 Ciclo. DOI 10.6092/unibo/amsdottorato/672.
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Assessment of brain connectivity among different brain areas during cognitive or motor tasks is a crucial problem in neuroscience today. Aim of this research study is to use neural mass models to assess the effect of various connectivity patterns in cortical EEG power spectral density (PSD), and investigate the possibility to derive connectivity circuits from EEG data. To this end, two different models have been built. In the first model an individual region of interest (ROI) has been built as the parallel arrangement of three populations, each one exhibiting a unimodal spectrum, at low, medium or high frequency. Connectivity among ROIs includes three parameters, which specify the strength of connection in the different frequency bands. Subsequent studies demonstrated that a single population can exhibit many different simultaneous rhythms, provided that some of these come from external sources (for instance, from remote regions). For this reason in the second model an individual ROI is simulated only with a single population. Both models have been validated by comparing the simulated power spectral density with that computed in some cortical regions during cognitive and motor tasks. Another research study is focused on multisensory integration of tactile and visual stimuli in the representation of the near space around the body (peripersonal space). This work describes an original neural network to simulate representation of the peripersonal space around the hands, in basal conditions and after training with a tool used to reach the far space. The model is composed of three areas for each hand, two unimodal areas (visual and tactile) connected to a third bimodal area (visual-tactile), which is activated only when a stimulus falls within the peripersonal space. Results show that the peripersonal space, which includes just a small visual space around the hand in normal conditions, becomes elongated in the direction of the tool after training, thanks to a reinforcement of synapses.

Tipologia del documento
Tesi di dottorato
Zavaglia, Melissa
Dottorato di ricerca
Settore disciplinare
Settore concorsuale
Parole chiave
neural network models brain connectivity eeg rhythms multisensory integration peripersonal space
Data di discussione
18 Aprile 2008

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