CMoS lab-on-a-chip devices for individual cell biology

Romani, Aldo (2005) CMoS lab-on-a-chip devices for individual cell biology, [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Ingegneria elettronica, informatica e delle telecomunicazioni, 17 Ciclo. DOI 10.6092/unibo/amsdottorato/15.
Documenti full-text disponibili:
Documento PDF (English) - Richiede un lettore di PDF come Xpdf o Adobe Acrobat Reader
Download (4MB) | Anteprima


The development of microlectronic lab-on-a-chip devices (LOACs) can now be pursued thanks to the continous advances in silicon technology. LOACs are miniaturized devices whose aim is to perform in a more efficient way specific chemical or biological analysis protocols which are usually carried out with traditional laboratory equipment. In this application area, CMOS technology has the potential to integrate LOAC functionalities for cell biology applications in single chips, e.g. sensors, actuators, signal conditioning and processing circuits. In this work, after a review of the state of the art, the development of a CMOS prototype chip for individual cell manipulation and detection based on dielectrophoresis will be presented. Issues related to the embedded optical and capacitive detection of cells will be discussed together with the main experimental results obtained in manipulation and detection of living cells and microparticles.

Tipologia del documento
Tesi di dottorato
Romani, Aldo
Dottorato di ricerca
Settore disciplinare
Settore concorsuale
Parole chiave
dielectrophoresis, capacitive sensors, optical sensors
Data di discussione
22 Aprile 2005

Altri metadati

Statistica sui download

Gestione del documento: Visualizza la tesi